4 min

How does the Kleresca treatment work against acne?

At Istituto Image, we conceive skin care as a scientific and personalized journey, aimed at restoring skin health and balance from within. We know that acne is not just a cosmetic issue, but a condition that can deeply affect psychophysical well-being. For this reason, we offer advanced therapeutic protocols that go beyond traditional treatments. Among our most innovative solutions, the Kleresca® treatment represents a true revolution in aesthetic dermatology, a non-invasive and clinically tested option to treat acne effectively and in full respect of the skin’s physiology. Kleresca Treatment: what it is and how it works The Kleresca® treatment marks a technological leap in modern dermatology, based on a unique scientific principle: biophotonic technology. Unlike lasers, peels, or topical drugs, Kleresca® does not act aggressively on the skin, but instead stimulates its natural repair mechanisms at the cellular level. Its functioning is based on the synergy of two key elements: A photoconverter gel : A patented chromophore gel is applied to the areas to be treated. This gel contains special pigments capable of converting light of a specific wavelength into fluorescent light energy. A multi-wavelength LED lamp : The skin is exposed for about nine minutes to the light of a high-intensity LED lamp. This light activates the gel, generating fluorescent light energy (FLE) that penetrates deep into the dermis. This light energy acts on multiple levels: it eliminates the bacteria responsible for acne ( Cutibacterium acnes ), reduces inflammation, normalizes cellular activity, and stimulates the production of new collagen. In practice, Kleresca® “teaches” the skin to repair itself, working with its biological processes and not against them. The benefits of Kleresca treatment for acne-prone skin The advantages of a treatment path with Kleresca® are multiple and go beyond the simple reduction of pimples. The biophotonic approach offers an overall improvement in skin health, with visible and lasting benefits. Anti-inflammatory and Antibacterial Action : The treatment reduces the inflammation that causes redness and swelling in acne lesions and eliminates P. acnes bacteria, addressing two of the main causes of acne. Stimulation of Collagen Production : Fluorescent light energy stimulates fibroblasts to produce new collagen. This not only improves skin texture but also helps repair and reduce the formation of post-acne scars. Normalization of Cellular Activity : The treatment helps rebalance sebum production, reducing the shiny effect typical of oily skin and minimizing the visibility of enlarged pores. Safety and Comfort : It is a non-invasive, painless procedure with no significant side effects. It does not cause photosensitivity, making it safe to perform at any time of the year, even in summer. To better understand its positioning compared to traditional methods, here is a comparative table: Kleresca® Mechanism of Action: stimulation of cellular regeneration through biophotonic energy. Invasiveness: non-invasive. Side Effects: minimal and transient (slight redness). Downtime: none, you can immediately resume daily activities. Year-Round Safety: safe all year, even in summer. Topical Treatments (Creams/Acids) Mechanism of Action: exfoliating or antibacterial chemical action on the skin’s surface. Invasiveness: generally non-invasive, but may cause irritation and dryness. Side Effects: irritation, dryness, peeling, photosensitivity. Downtime: variable, from none to a few days of peeling. Year-Round Safety: often discouraged in summer due to photosensitivity. Oral Therapies (Antibiotics/Isotretinoin) Mechanism of Action: systemic action to reduce bacteria, inflammation, or sebum production. Invasiveness: systemic invasiveness, with possible side effects throughout the body. Side Effects: severe dryness, photosensitivity, gastrointestinal issues, need for medical monitoring. Downtime: none, but side effects may persist. Year-Round Safety: require strict medical supervision and are often unsuitable for long-term use. The Kleresca treatment process: what to expect during the session A Kleresca® session is a comfortable and relaxing experience, carried out in the clinic under the supervision of our specialized therapists. The protocol is simple and well-structured: Cleansing : The skin is thoroughly cleansed to remove any trace of makeup and impurities, preparing it for treatment. Gel Application : The Kleresca® photoconverter gel is applied in an even layer to the affected areas (face, neck, or décolleté). LED Light Exposure : The patient sits under the LED lamp for about 9 minutes. During this phase, a pleasant warmth and intense light are perceived, for which protective glasses are provided. Removal and Hydration : At the end of the exposure, the gel is gently removed and a soothing moisturizing cream is applied to complete the treatment. The entire session lasts about 30 minutes. No anesthesia is needed, and patients can immediately resume daily activities after the treatment. Expected results of Biophotonic therapy: how long before improvements? Kleresca® results are progressive and continue to improve over time, even after the treatment cycle ends. The effectiveness of biophotonic therapy lies in its ability to stimulate deep regeneration, which requires time to fully manifest. A standard acne protocol typically includes 4–6 sessions, carried out weekly or bi-weekly. The first improvements, such as reduced inflammation and redness, are often visible after the first few sessions. As the treatment progresses, a decrease in active lesions and an improvement in skin texture are observed. Collagen production benefits continue for months after the last session, resulting in firmer, smoother skin with diminished scars. Patience and consistency are rewarded with natural and long-lasting results. Safety considerations and possible side effects Safety is one of Kleresca®’s strengths. Being a non-invasive and non-systemic procedure, it does not carry the risks associated with drugs or aggressive laser treatments. The treatment is clinically tested and considered very safe. Side effects are rare, mild, and temporary. Some patients may experience slight redness or minimal temporary hyperpigmentation in treated areas, which usually resolve within hours or days. No specific preparation is required before the session and, as mentioned, there is no downtime, making it easy to integrate the treatment into a weekly routine. Why choose istitutoimage.it for the Kleresca treatment Choosing Istituto Image means relying on a team of professionals who believe in an integrated, scientific approach to acne care. We do not limit ourselves to performing a single treatment, but build a complete and personalized journey. Our acne protocol, supervised by doctors and therapists, often combines the action of Kleresca® with other synergistic methods to maximize results: Hydrafacial® : As a preparatory treatment, it performs deep cleansing and hydration, making the skin more receptive to biophotonic therapy. Chemical Peels : Used alternately or after the Kleresca® cycle, they help refine skin texture and treat post-inflammatory spots. Oxygen Ozone Therapy : Its antibacterial and regenerative properties enhance Kleresca®’s effect, accelerating tissue healing. Every journey is completed with a home therapy plan using specific cosmeceutical products, designed to maintain and enhance the results obtained in the clinic. This 360-degree approach ensures not only the resolution of blemishes but also the achievement of optimal and lasting skin health. Are you tired of the usual treatments that irritate the skin without giving lasting results? Biophotonic Kleresca® therapy is a true revolution: a non-invasive method that stimulates your skin to regenerate and fight acne from within, without side effects. It’s time to try a different approach, based on your skin’s biology. Book a specialist consultation at Istituto Image and discover how our personalized Kleresca® protocol can give you healthy, radiant skin. FAQ What are the contraindications of the Kleresca treatment? Kleresca® treatment is very safe, but it is generally contraindicated in cases of pregnancy, epilepsy, or if taking photosensitizing drugs. A preliminary consultation with a specialist is always required to assess treatment suitability. What is the most effective cure for acne? The most effective cure is the personalized one. For inflammatory and persistent acne, a non-invasive approach like Kleresca® has proven highly effective because it addresses the causes (inflammation and bacteria) and stimulates skin regeneration, preventing scars. Maximum effectiveness is achieved by integrating the treatment into a medical protocol that also includes other therapies and proper home skincare. What is the Kleresca method? The Kleresca® method is a non-invasive biophotonic therapy that uses the combination of a photoconverter gel and LED light to generate fluorescent light energy. This energy penetrates deep into the skin, reducing inflammation, eliminating bacteria, and stimulating collagen production to treat acne and improve skin health. How can acne be permanently eliminated? Acne is a chronic condition that requires a long-term approach. To manage it permanently, an integrated medical plan that addresses both internal and external causes is needed. Protocols combining advanced therapies like Kleresca®, peels, and a proper home routine, together with a healthy lifestyle, offer the most stable and lasting results. What is the Kleresca® rosacea treatment? It is a specific formulation of the Kleresca® protocol, designed to treat rosacea symptoms. It works by reducing inflammation, redness, and papulo-pustular lesions typical of this condition. Biophotonic therapy helps calm reactive skin and improve microcirculation, offering relief and enhancing the skin’s appearance.

5 min

Knee Osteoarthritis Treatment with Stem Cells: The Lipogems Solution

Knee osteoarthritis, or gonarthrosis, is a degenerative condition that affects millions of people, undermining quality of life with pain, stiffness, and movement limitations. If you've been diagnosed with it or live daily with these symptoms, you know how frustrating it can be. Traditional therapies, such as hyaluronic acid injections, often offer only temporary relief. But today, the frontier of medicine has shifted toward a more promising horizon: regeneration. At Istituto Image, under the scientific guidance of Professor Carlo Tremolada, a pioneer in this field, we offer a revolutionary approach to treating knee osteoarthritis. Through the minimally invasive Lipogems methodology for knee osteoarthritis , we harness your own body's regenerative potential to address the problem at its root, offering an effective and lasting solution, often with a single application. What is Knee Osteoarthritis: Main Causes and Symptoms Knee osteoarthritis is a chronic condition that develops when cartilage, the smooth and elastic tissue covering the ends of bones in the joint, progressively wears down. This protective layer, as it thins, loses its ability to cushion movements, causing bone surfaces to rub against each other. The causes are multifactorial and include: Aging: Natural wear and tear is one of the main factors. Overweight and obesity: Excess weight increases the load on knees, accelerating cartilage deterioration. Previous trauma: Fractures, ligament injuries (such as ACL) or meniscus damage can trigger post-traumatic arthritic processes. Genetic factors: There is a family predisposition to developing the condition. Demanding work or sports activities: Professions or sports involving repeated joint overload. Initial symptoms are often mild and intermittent, later becoming more constant and debilitating. The most common include: Pain: Initially present during movement, like climbing stairs or after exertion, it can become constant even at rest or during the night. Joint stiffness: Especially in the morning or after long periods of inactivity. Swelling: Often associated with joint effusion. Functional limitation: Difficulty fully bending or extending the knee. Crackling and crunching: Sensation of "sand" inside the joint during movement. Osteoarthritis Diagnosis: When to Consider Lipogems Treatment An accurate diagnosis is the fundamental first step. The journey begins with a specialist orthopedic consultation, during which the doctor will evaluate the patient's clinical history and knee joint mobility. Instrumental examinations like X-rays are essential to confirm the diagnosis, showing joint space reduction and the presence of any osteophytes (small bone growths). In some cases, an MRI may be requested to assess soft tissue status, such as menisci and ligaments. The choice to consider Lipogems® treatment emerges as the option of choice at a specific point in the patient's therapeutic journey. Typically, this occurs when conservative strategies, such as physical therapy or anti-inflammatory drugs, can no longer offer adequate pain control, leaving the person in a state of chronic suffering. Similarly, many patients turn to us after experiencing the limitations of hyaluronic acid injections, which, while offering relief, prove to be a temporary solution with benefits that vanish within 3-6 months, requiring repeated treatment cycles. Lipogems® therefore presents itself as the ideal solution for those seeking a biological and natural approach that directly taps into their body's self-healing potential. It represents a concrete strategy for those who want to postpone, and in many cases avoid, the need for invasive surgical intervention such as knee prosthesis implantation. How Do Stem Cell Injections for the Knee Work? Lipogems® is not a simple injection, but a true regenerative medicine treatment. The procedure, devised and patented by Professor Carlo Tremolada, is based on using adipose tissue harvested from the patient themselves, a biological resource extraordinarily rich in mesenchymal (stem) cells and pericytes, key elements for tissue regeneration. The process is minimally invasive and takes place in a single outpatient session: Harvesting: Through a small liposuction performed under local anesthesia, a minimal amount of adipose tissue is collected, usually from the abdomen or flanks. Processing: The harvested fat is inserted into the Lipogems® device, a closed and sterile system that, through a mechanical micro-fragmentation process, purifies the tissue, eliminating oily and inflammatory components and concentrating cells with high regenerative potential. Injection: The purified and activated tissue is then injected directly into the knee joint, under ultrasound guidance to ensure maximum precision. Once injected, these cells act as a natural "repair team," releasing growth factors and anti-inflammatory cytokines that orchestrate a regeneration process. Benefits and Results: What to Expect from Treatment Unlike hyaluronic acid, which acts primarily as a lubricant with a temporary effect, Lipogems® promotes true biological healing. The benefits are concrete and lasting: Anti-inflammatory Action: The injected cells modulate the joint's inflammatory environment, leading to rapid and significant pain reduction. Regeneration Stimulation: Released growth factors stimulate cartilage cells to repair themselves, slowing the degenerative process. Functionality Improvement: Reduced pain and inflammation translate into improved mobility, flexibility, and ability to walk without limitations. Results are not only immediate but progressive. Many patients experience significant relief within the first weeks, with benefits that continue to consolidate in subsequent months and can last for years, often with a single application. Lipogems Treatment: Procedures, Duration, and Precautions The Lipogems® procedure is performed on an outpatient basis and has a total duration of about 60 minutes. It's a safe technique, as it uses the patient's own tissue (autologous), eliminating any risk of rejection or allergic reaction. Precautions: Before treatment, a specialist evaluation is essential to confirm the patient's suitability. After the procedure, a brief period of relative rest is recommended, avoiding excessive loads on the joint for the first few days. Return to normal daily activities is generally very quick. Lifestyle and Tips to Enhance Treatment Effectiveness To maximize and extend the benefits of Lipogems® treatment, it's essential to adopt a healthy lifestyle. Although our approach is aimed at regenerating from within, some precautions can make a big difference: Weight Control: Maintaining adequate body weight reduces the load on the knee joint, decreasing mechanical stress and slowing cartilage wear. Low-Impact Physical Activity: Sports like swimming, cycling, or walking on flat surfaces are ideal for maintaining joint mobility, strengthening thigh musculature (which acts as a natural shock absorber for the knee) without overloading the joint. Anti-inflammatory Diet: A diet rich in fruits, vegetables, omega-3 fatty acids (found in oily fish and nuts) and low in refined sugars and processed foods can help reduce systemic inflammation, supporting the healing process. Targeted Physical Therapy: A personalized rehabilitation program, developed in synergy with regenerative treatment, is crucial for recovering full functionality, improving balance and posture. Addressing knee osteoarthritis today means looking beyond palliative solutions. Regenerative medicine with Lipogems® offers a concrete possibility to change the course of the pathology, not only managing symptoms but promoting deep and lasting healing. Autologous and micro-fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis (A. Russo et al., 2017) Minimally manipulated adipose derived mesenchymal stromal cells and osteoarthritis: A narrative review Successful isolation of viable stem cells from cryopreserved microfragmented human adipose tissue … Micro-fragmented adipose tissue injection associated with arthroscopic procedures in patients with symptomatic knee osteoarthritis (G. Cattaneo et al., 2018) Frequently Asked Questions (FAQ) How long does it take to see effects in the knee? The first benefits in terms of pain and inflammation reduction can be felt just a few weeks after treatment. However, the regenerative process is gradual: results continue to improve progressively over the next 3-6 months, with benefits that can last for years. How much does regenerative medicine technique for the knee cost? The cost of Lipogems® treatment is defined following a specialist medical evaluation, as it depends on the patient's specific condition and case complexity. It's important to note that, being a therapeutic procedure for orthopedic purposes, in many cases it's reimbursed by major private health insurance companies. How much should you walk with knee osteoarthritis? Physical activity is fundamental, but it must be low-impact. Walking on flat and soft surfaces is recommended, avoiding steep ascents or descents. A 20-30 minute walk per day is generally beneficial for maintaining mobility and strengthening muscles.